Results 171 to 180 of about 94,759 (256)

Sequencing and Optical Genome Mapping for the Adventurous Chemist. [PDF]

open access: yesChem Biomed Imaging
Ruppeka Rupeika E   +3 more
europepmc   +1 more source

Bioactive siRNA‐Based Liposomes Promoted Tendon‐Bone Healing in Osteoporotic Mice by Recovering the Stemness of CD248+ TSPCs

open access: yesAdvanced Science, EarlyView.
In this study, it is found that osteoporosis leads to disturbances in the Extracellular Matrix (ECM)of tendons and thus causes a decrease in TSPC stemness, resulting in a rotator cuff that is easily damaged and prone to retearing after repair. Targeted intervention with si‐CD248‐loaded liposomes can restore TSPC stemness, promote tendon‐bone healing ...
Yinhua Qian   +14 more
wiley   +1 more source

Rabbit Hepatitis E Virus, Ukraine, 2024. [PDF]

open access: yesEmerg Infect Dis
Santos-Silva S   +7 more
europepmc   +1 more source

A Splice‐Region Variant Causes an Atypical Presentation of GNAS Inactivation Disorder

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in GNAS can cause a wide range of diseases including pseudohypoparathyroidism, pseudopseudohypoparathyroidism, McCune‐Albright syndrome, among others. The specific phenotypic features that may be seen are influenced by the variant type and location in the gene, whether it causes loss or gain of function, and whether it is ...
Brandon S. Stone   +11 more
wiley   +1 more source

Development of a Dual-Index Sequencing Strategy and Curation Pipeline for Analyzing Amplicon Sequence Data on the MiSeq Illumina Sequencing Platform

open access: yesApplied and Environmental Microbiology, 2013
James J Kozich   +4 more
semanticscholar   +1 more source

Long noncoding RNA GCH1 mediates mitophagy via the PTEN‐induced kinase 1/Parkin pathway to drive chondrocyte dysfunction and cartilage degeneration in osteoarthritis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract illustrates the role of lncRNA‐GCH1 in regulating mitophagy and its downstream effects on chondrocyte dysfunction and cartilage degradation in osteoarthritis (OA). Elevated lncRNA‐GCH1 stabilizes PINK1 protein, enhancing mitophagy and mitochondrial turnover.
Gang Zeng   +8 more
wiley   +1 more source

The promising role of nanopore sequencing in cancer diagnostics and treatment. [PDF]

open access: yesCell Insight
Su X   +8 more
europepmc   +1 more source

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