High throughput genomic sequencing of bioaerosols in broiler chicken production facilities [PDF]
, 2016 Chronic inhalation exposure to agricultural dust promotes the development of chronic respiratory diseases among poultry workers. Poultry dust is composed of dander, chicken feed, litter bedding and microbes.
Bair, Thomas +6 more
core +2 more sources
3127 The effect of common genetic variants in the oxytocin receptor gene on oxytocin response.
Journal of Clinical and Translational Science, 2019 OBJECTIVES/SPECIFIC AIMS: Previous studies suggest that genetic variants in the oxytocin receptor (OXTR) may alter oxytocin dose requirement for labor induction and may increase risk for preterm labor and neurodevelopmental disorders.
Manasi Malik +6 more
doaj +1 more source
Whole-exome analysis in osteosarcoma to identify a personalized therapy [PDF]
, 2017 Osteosarcoma is the most common pediatric primary non-hematopoietic bone tumor. Survival of these young patients is related to the response to chemotherapy and development of metastases.
Aretini, Paolo +13 more
core +1 more source
Human presence impacts fungal diversity of inflated lunar/Mars analog habitat
Microbiome, 2017 Background An inflatable lunar/Mars analog habitat (ILMAH), simulated closed system isolated by HEPA filtration, mimics International Space Station (ISS) conditions and future human habitation on other planets except for the exchange of air between ...
A. Blachowicz +5 more
doaj +1 more source
Scientific Reports, 2017 Base-calling accuracy is crucial for high-throughput DNA sequencing and downstream analysis such as read mapping and genome assembly. Accordingly, we made an endeavor to reduce DNA sequencing errors of Illumina systems by correcting three kinds of ...
Bo Wang, Lin Wan, Anqi Wang, Lei M. Li
semanticscholar +1 more source
C/EBPα-p30 protein induces expression of the oncogenic long non-coding RNA UCA1 in acute myeloid leukemia [PDF]
, 2015 Accumulating evidences indicate that different long non-coding RNAs (lncRNAs) might play a relevant role in tumorigenesis, with their expression and function already associated to cancer development and progression.
Bozzoni, Irene +8 more
core +2 more sources
Scientific Reports, 2017 This study investigated the efficiency of nanoscale zero-valent iron combined with persulfate (NZVI/PS) for enhanced degradation of brilliant red X-3B in an upflow anaerobic sludge blanket (UASB) reactor, and examined the effects of NZVI/PS on anaerobic ...
Fei Pan +7 more
semanticscholar +1 more source
DNMT inhibitors reverse a specific signature of aberrant promoter DNA methylation and associated gene silencing in AML [PDF]
, 2014 <b>Background</b>. Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) are neoplastic disorders of hematopoietic stem cells. DNA methyltransferase inhibitors (DNMTi), 5-azacytidine (AzaC) and 5-aza-2’-deoxycytidine (Decitabine),
Adams, Peter +8 more
core +2 more sources
A novel NGS library preparation method to characterize native termini of fragmented DNA. [PDF]
, 2020 Biological and chemical DNA fragmentation generates DNA molecules with a variety of termini, including blunt ends and single-stranded overhangs. We have developed a Next Generation Sequencing (NGS) assay, XACTLY, to interrogate the termini of fragmented ...
Green, Richard E +7 more
core +1 more source
BM-BC: A Bayesian Method of Base Calling for Solexa Sequence Data [PDF]
, 2012 Base calling is a critical step in the Solexa next-generation sequencing procedure. It compares the position-specific intensity measurements that reflect the signal strength of four possible bases (A, C, G, T) at each genomic position, and outputs ...
Jara, Alejandro +7 more
core +2 more sources