Draft genome sequencing of multidrug-resistant <i>Klebsiella pneumoniae</i> from neonatal bloodstream infections at SRHU, Dehradun, India. [PDF]
Sarkar I +4 more
europepmc +1 more source
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
Draft genome sequence of plant growth-promoting bacterial endophyte <i>Cellulosimicrobium cellulans</i> strain MUKR 5 isolated from <i>Iris laevigata</i> Fisch. from Manipur, India. [PDF]
Thokchom S, Mukherjee S, Ningthoujam DS.
europepmc +1 more source
SJNPs co‐deliver JHU083 and spermine to reprogram macrophage–neuron immunometabolic crosstalk in sepsis. By suppressing pro‐inflammatory M1 polarization and promoting NGF‐mediated neurotrophic signaling, SJNPs preserve pulmonary neuronal integrity, alleviate lung injury, and improve survival in murine sepsis models.
Wenhui Wang +11 more
wiley +1 more source
Complete genome sequences of two dye-decolorizing aeromonads isolated from a stormwater drain in Hong Kong. [PDF]
Leung PSK +3 more
europepmc +1 more source
H2S‐Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety
Albumin nanoparticles loaded with an H2S‐releasing aspirin derivative (ACS14) hitchhiking neutrophils after intraperitoneal injection and preferentially accumulate in endometriosis lesions in mice. The treatment suppresses lesion growth by regulating PI3K/Akt and reduces inflammation by inhibiting NF‐κB.
Mengni Zhou +12 more
wiley +1 more source
Complete genome sequences of two strains of <i>Pseudomonas fragi</i>, isolated from feces of a domestic rabbit (<i>Oryctolagus cuniculus</i>). [PDF]
Chow LKY +4 more
europepmc +1 more source
Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu +23 more
wiley +1 more source
Metagenomic and microbiological analyses of historical manuscripts for bacterial community profiling and bacteria-related biodeterioration assessment. [PDF]
Keles E, Celik O.
europepmc +1 more source
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu +15 more
wiley +1 more source

