Results 201 to 210 of about 554,389 (266)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Multi-scale studies of oil-water imbibition mechanism on complex pore structures and mixed-wettability: a recent 10-year review. [PDF]

Sci Rep
Liu Q, Wang Q, Liang B, Sun W, Jin J, Liu J, Lei Y, Gao J.   +7 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Smart contact lens-trained digital twin for device-free personalized uric acid prediction. [PDF]

Sci Adv
Song H, Hong YM, Kim D, Seo H, Park W, Paek J, Lee D, Cho SK, Ahn SS, Kim J, Park JU.   +10 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

When Ebstein Meets Fallot: A Right-Sided ECG Puzzle. [PDF]

JACC Case Rep
Ader J, Bredy C, Pasquié JL.
europepmc   +1 more source

MEDICAL ILLUSTRATION

International Journal of Clinical Practice, 1953
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Spontaneous Rupture of a Peritonsillar Abscess Mimicking Successful Incision and Drainage: A Case Report. [PDF]

Cureus
Alshamsi RRMBS, Horani S, Sami Alhammadi F, Al Salhani T.   +3 more
europepmc   +1 more source