Results 41 to 50 of about 70,187 (299)

MR-CBCT image-guided system for radiotherapy of orthotopic rat prostate tumors. [PDF]

PLoS ONE, 2018
Multi-modality image-guided radiotherapy is the standard of care in contemporary cancer management; however, it is not common in preclinical settings due to both hardware and software limitations.
Tsuicheng D Chiu, Tatsuya J Arai, James Campbell Iii, Steve B Jiang, Ralph P Mason, Strahinja Stojadinovic   +5 more
doaj   +1 more source

Is Diffusion Tensor Imaging-Guided Radiotherapy the New State-of-the-Art? A Review of the Current Literature and Technical Insights

Applied Sciences, 2022
Despite the increasing precision of radiotherapy delivery, it is still frequently associated with neurological complications. This is in part due to damage to eloquent white matter (WM) tracts, which is made more likely by the fact they cannot be ...
Jordan Colman, Laura Mancini, Spyros Manolopoulos, Meetakshi Gupta, Michael Kosmin, Sotirios Bisdas   +5 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Current advances in radiotherapy for soft tissue sarcomas

Nowotwory, 2020
Radiotherapy (RT) is a part of the routine treatment of locally advanced or high-grade soft-tissue sarcomas (STS). However, RT has changed significantly over the last 20 years. Modern RT techniques have extended its potential application in STS treatment.
Mateusz J. Spałek, Aneta M. Borkowska
doaj   +1 more source

Leaf-individual calibration for a double stack multileaf collimator in photon radiotherapy

Physics and Imaging in Radiation Oncology, 2023
Background and Purpose: In online adaptive stereotactic body radiotherapy treatments, linear accelerator delivery accuracy is essential. Recently introduced double stack multileaf collimators (MLCs) have new facets in their calibration.
Carolin Rippke, C. Katharina Renkamp, Charbel Attieh, Fabian Schlüter, Carolin Buchele, Jürgen Debus, Markus Alber, Sebastian Klüter   +7 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

A comparison of treatment outcome between fiducial-based and bone-based image guided radiotherapy in prostate cancer patients

Radiation Oncology, 2018
Background and purpose To compare the clinical outcome in prostate cancer patients treated with radiotherapy using two forms of image guidance: bone-based (BB) or fiducial-based (FB).
Aleksandra Napieralska, Wojciech Majewski, Roland Kulik, Grzegorz Głowacki, Leszek Miszczyk   +4 more
doaj   +1 more source

Mechanical high-intensity focused ultrasound creates unique tumor debris enhancing dendritic cell-induced T cell activation

Frontiers in Immunology, 2022
IntroductionIn situ tumor ablation releases a unique repertoire of antigens from a heterogeneous population of tumor cells. High-intensity focused ultrasound (HIFU) is a completely noninvasive ablation therapy that can be used to ablate tumors either by ...
Renske J. E. van den Bijgaart, Vera E. Mekers, Fabian Schuurmans, Tonke K. Raaijmakers, Melissa Wassink, Andor Veltien, Erik Dumont, Arend Heerschap, Jurgen J. Fütterer, Jurgen J. Fütterer, Gosse J. Adema   +10 more
doaj   +1 more source

Accurate,robust and harmonized implementation of morpho-functional imaging in treatment planning for personalized radiotherapy [PDF]

, 2019
In this work we present a methodology able to use harmonized PET/CT imaging in dose painting by number (DPBN) approach by means of a robust and accurate treatment planning system.
Baeza, José Antonio, Balcerzyk, Marcin, García-Gómez, Francisco Javier, Jiménez Ortega, Elisa Eugenia, Leal Plaza, Antonio, Parrado-Gallego, Ángel, Pereira Barbeiro, Ana Rita, Ureba Sánchez, Ana María, Wals-Zurita, Amadeo   +8 more
core   +2 more sources