Deformable Shape Priors in Chan-Vese Segmentation of Image Sequences
, 2007 In this paper we propose a new method for variational segmentation of image sequences containing nonrigid, moving objects. The method is based on the Chan-Vese model augmented with a novel frame-to-frame interaction term, which allow us to update the ...
Niels Chr. Overgaard +8 more
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Image Translation and Reconstruction Using a Single Dual Mode Lightweight Encoder
IEEE AccessThe richness of textures and semantic information from RGB images can be supplemented in computer vision by the robustness of thermal images to light variations and weather artifacts.
Jose Amendola +2 more
doaj +1 more source
Addressing inter-device variations in optical coherence tomography angiography: will image-to-image translation systems help? [PDF]
Int J Retina Vitreous, 2023 Nouri H, Nasri R, Abtahi SH.
europepmc +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
GAN-Based Map Generation Technique of Aerial Image Using Residual Blocks and Canny Edge Detector
Applied SciencesAs the significance of meticulous and precise map creation grows in modern Geographic Information Systems (GISs), urban planning, disaster response, and other domains, the necessity for sophisticated map generation technology has become increasingly ...
Jongwook Si, Sungyoung Kim
doaj +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Progressively Unsupervised Generative Attentional Networks with Adaptive Layer-Instance Normalization for Image-to-Image Translation. [PDF]
Sensors (Basel), 2023 Lee HY, Li YH, Lee TH, Aslam MS.
europepmc +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source