Results 201 to 210 of about 13,865,362 (341)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Imaging of Pulmonary Sarcoidosis—A Review [PDF]

Georgina L. Bailey, Athol U. Wells, Sujal R. Desai   +2 more
openalex   +1 more source

Mortalin imaging in normal and cancer cells with quantum dot immuno-conjugates [PDF]

, 2003
Zeenia Kaul, Tomoko Yaguchi, Sunil C. Kaul, Takashi Hirano, Renu Wadhwa, Kazunari Taira   +5 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Sternal Foramina Detected by Postmortem Computed Tomography in the Japanese Population: Prevalence and Developmental Patterns

Radiology Research and Practice
Akihito Usui, Sonoka Sato, Eiji Suzuki, Sohtaro Mimasaka, Tomohiro Kaneta   +4 more
doaj   +1 more source

Low-Light Image Segmentation on Edge Computing System. [PDF]

Sensors (Basel)
Choi SC, Kim SY.
europepmc   +1 more source

Diagnostic Value of Right Ventricular Dysfunction in Tachycardia-Induced Cardiomyopathy Using Cardiac Magnetic Resonance Imaging

, 2016
Atsushi Okada, Ikutaro Nakajima, Yoshiaki Morita, Yuko Inoue, Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, Koji Miyamoto, Hideo Okamura, Satoshi Nagase, Takashi Noda, Takeshi Aiba, Shiro Kamakura, Toshihisa Anzai, Teruo Noguchi, Satoshi Yasuda, Kengo Kusano   +16 more
openalex   +2 more sources

Artifact reduction in true‐FISP imaging of the coronary arteries by adjusting imaging frequency [PDF]

, 2003
Vibhas Deshpande, Steven M. Shea, Debiao Li   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Effects of Image Degradation on Deep Neural Network Classification of Scaphoid Fracture Radiographs: Comparison Study of Different Noise Types.

JMIR Med Inform
Lin C, Yoon AP, Wang CW, Chao T, Chung KC, Kuo CF.   +5 more
europepmc   +1 more source