Results 241 to 250 of about 13,865,268 (312)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Image-Based Pore Space and Pore Network Characterization: A Review of 2D/3D Workflow in Foods. [PDF]

J Food Sci
Luka BS, Ibrahim AG, Muhammed IB, Yunusa BM, Siddiqui MH, Osama K.   +5 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Gate-Tunable Polarity-Reconfigurable Photovoltaic Response With Dual Linearity in NbS₃/WSe₂ Heterostructures for In-Sensor Image Processing. [PDF]

Adv Sci (Weinh)
Liu J, Xie J, Hao Q, Hu Y, He Z, Liu H, Lin D, Gan H, Tu Y, Zhang W.   +9 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Workflow evaluation of a commercial deep learning-based image analysis tool for the quantification of angiogenesis in vivo. [PDF]

Sci Rep
Buhr CR, Maas AP, Wiesmann-Imilowski N, Brieger J, Matthias C, Ernst BP, Kloss-Brandstaetter A, Herrmann P, Eckrich J.   +8 more
europepmc   +1 more source

DEMANet: A dehazing enhanced multi-branch attention network for remote sensing images. [PDF]

PLoS One
Liu P, Liu S, He P, Wang G.
europepmc   +1 more source

6-Gingerol Regulates the Exosomal miR-148b-3p/ACSL4/Ferroptosis Axis in an in vitro Model of Diabetic Retinopathy. [PDF]

Diabetes Metab Syndr Obes
Liu S, Ye J, Suo L, Xu T, Chen Y, Liu W.
europepmc   +1 more source

A multi-category eye image dataset for AI-based segmentation and analysis of eyelid disorders. [PDF]

Sci Data
Shao J, Cao J, Wang C, Xu P, Zhang X, Sun Y, Chen P, Dai N, Lou L, Ye J.   +9 more
europepmc   +1 more source