Results 71 to 80 of about 10,352,216 (337)
BMC Ophthalmology, 2018 Background The corneal epithelium is directly affected in dry eye syndrome. Thus, we attempted to describe the morphological features and evaluate the cellular density within the corneal epithelial layers in patients with non-Sjögren’s (NSDE) and Sjögren’
Olivia L. Lee +6 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Plant, Cell & Environment, 2017 A silicon‐integrated MXene X‐ray detector exhibits high sensitivity and an ultra‐low detection limit, enabling clear and precise single‐pixel X‐ray imaging ...
Vassiliki Mpakou +20 more
openaire +1 more source
Actively pulse shaped linearly polarized nanosecond hybrid Ho3+ and Tm3+-doped silica fiber & Ho3+:YAG MOPA at 2048 nm [PDF]
EPJ Web of ConferencesHo3+:YAG amplifiers are able to efficiently scale pulse energy at wavelengths far shorter than the main emission peak. For 24 W input power at 2048 nm a signal output power of 81.6 W is reached, resulting in 5.3 dB gain.
Lorenz Dominik +8 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Development and validation of a novel porcine bile duct dilation model for EUS training
Endoscopy International Open, 2022 Background and study aims Image-guided minimally invasive techniques have transformed the management of malignant and benign bile duct obstructions. These evolving techniques are being widely adopted and applied and hands-on training using high quality ...
Leonardo Sosa-Valencia +5 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Impact of image quality on OCT angiography based quantitative measurements
International Journal of Retina and Vitreous, 2017 Background To study the impact of image quality on quantitative measurements and the frequency of segmentation error with optical coherence tomography angiography (OCTA). Methods Seventeen eyes of 10 healthy individuals were included in this study.
Mayss Al-Sheikh +3 more
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source