Results 71 to 80 of about 2,449,137 (268)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Multitemporal Cloud Masking in the Google Earth Engine
Remote Sensing, 2018 The exploitation of Earth observation satellite images acquired by optical instruments requires an automatic and accurate cloud detection. Multitemporal approaches to cloud detection are usually more powerful than their single scene counterparts since ...
Gonzalo Mateo-García +4 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Intelligent MedicineBackground With the gradual increase of infertility in the world, among which male sperm problems are the main factor for infertility, more and more couples are using computer-assisted sperm analysis (CASA) to assist in the analysis and treatment of ...
Ao Chen +11 more
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Clinical and MRI Features of Tumors of Septum Pellucidum
Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the clinical and magnetic resonance imaging (MRI) features of the tumors of septum pellucidum. Methods We analyzed retrospectively the clinical data of 45 patients with the tumors of septum pellucidum confirmed by operation and ...
HAO Ni'na +4 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Nature, 1987 In a Mössbauer experiment, if a spatially-extended absorbing sample is rotated relative to a moving γ-ray source, lines of constant γ-ray Doppler shift are generated through the absorber parallel to the motion of the source. As a result, resonant absorption takes place along a series of parallel lines cutting through the absorber, where a particular ...
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Causal discovery reveals complex patterns of drought-induced displacement
iScienceSummary: The increasing frequency and severity of droughts present a significant risk to vulnerable regions of the globe, potentially leading to substantial human displacement in extreme situations.
Jose María Tárraga +8 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source