Results 81 to 90 of about 13,865,362 (341)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Image segmentation based on adaptive K-means algorithm
EURASIP Journal on Image and Video Processing, 2018 Image segmentation is an important preprocessing operation in image recognition and computer vision. This paper proposes an adaptive K-means image segmentation method, which generates accurate segmentation results with simple operation and avoids the ...
Xin Zheng +4 more
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The Montage Image Mosaic Service: Custom Image Mosaics On-Demand [PDF]
, 2008 The Montage software suite has proven extremely useful as a general engine for reprojecting, background matching, and mosaicking astronomical image data from a wide variety of sources. The processing algorithms support all common World Coordinate System (
Berriman, G. B. +3 more
core
Imaging Informatics: from Image Management to Image Navigation [PDF]
Yearbook of Medical Informatics, 2009 Summary Objective To review the rapid evolution of imaging informatics dealing with issues of management and communication of digital images starting from the era of simple storage and transfer of images to today’s world of interactive navigation in large sets of multidimensional data.
openaire +2 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Clinical and MRI Features of Tumors of Septum Pellucidum
Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the clinical and magnetic resonance imaging (MRI) features of the tumors of septum pellucidum. Methods We analyzed retrospectively the clinical data of 45 patients with the tumors of septum pellucidum confirmed by operation and ...
HAO Ni'na +4 more
doaj +1 more source