Results 91 to 100 of about 11,974,913 (292)

Report to the Governor from the Mental Health Alignment Workgroup: executive summary

open access: yes, 2001
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF title page (viewed on May 7, 2009)At head of ...

core  

Global Network Alignment [PDF]

open access: yes, 2010
Motivation: High-throughput methods for detecting molecular interactions have lead to a plethora of biological network data with much more yet to come, stimulating the development of techniques for biological network alignment.
Oleksii Kuchaiev, Natasa Przulj
core  

Statistical analysis of alignment characteristics for phrase-based machine translation [PDF]

open access: yes, 2010
In most statistical machine translation (SMT) systems, bilingual segments are extracted via word alignment. However, there lacks systematic study as to what alignment characteristics can benefit MT under specific experimental settings such as the ...
Petitrenaud, Simon   +7 more
core   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Alignment

open access: yes, 2013
Following 454 sequencing of the 16s rDNA region of bacterial communities of 59 samples of attine ants, 35,063 unique sequences were identified after data quality check.
Lars H. Hansen (129876)   +3 more
core   +1 more source

Divide-and-conquer multiple alignment with segment-based constraints [PDF]

open access: yes, 2003
Sammeth M, Morgenstern B, Stoye J. Divide-and-conquer multiple alignment with segment-based constraints. BIOINFORMATICS. 2003;19(Suppl 2):ii189-ii195.A large number of methods for multiple sequence alignment are currenty available.
Sammeth, Michael   +2 more
core   +1 more source

A Novel Image Alignment Algorithm Based on Rotation-Discriminating Ring-Shifted Projection for Automatic Optical Inspection

open access: yesApplied Sciences, 2016
This paper proposes a novel image alignment algorithm based on rotation-discriminating ring-shifted projection for automatic optical inspection. This new algorithm not only identifies the location of the template image within an inspection image but also
Chin-Sheng Chen, Chien-Liang Huang
doaj   +1 more source

Reimagining Safety Alignment with An Image

open access: yesProceedings of the 2025 Conference on Empirical Methods in Natural Language Processing
Large language models (LLMs) excel in diverse applications but face dual challenges: generating harmful content under jailbreak attacks and over-refusal of benign queries due to rigid safety mechanisms. These issues are further complicated by the need to accommodate different value systems and precisely align with given safety preferences.
Yifan Xia   +5 more
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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