Results 151 to 160 of about 330,202 (308)
3D Model Retrieval by Sample Based Alignment [PDF]
[[abstract]]In 3D model retrieval, preprocessing of 3D models is needed, in which alignment is a key factor that significantly affects retrieval performance. In particular, the anti-rotation image feature can obtain the alignment effect of 3D model views.
Chen, Z.-Y.;Chen, Zong-Yao;林維昭;Lin, Wei-Chao;Ts, Chih-Fong;Tsai, Chih-Fong;*;Ke, Shih-Wen;Ke, Shih-Wen
core
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Multi-Scale Image- and Feature-Level Alignment for Cross-Resolution Person Re-Identification [PDF]
Cross-Resolution Person Re-Identification (re-ID) aims to match images with disparate resolutions arising from variations in camera hardware and shooting distances.
Jiangmei Zhang +4 more
core +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Living with the Semantic Gap: Experiences and remedies in the context of medical imaging [PDF]
Semantic annotation of images is a key concern for the newly emerged applications of semantic multimedia. Machine processable descriptions of images make it possible to automate a variety of tasks from search and discovery to composition and collage of ...
Kalfoglou, Yannis +5 more
core
Enhancement of RGB-D Image Alignment Using Fiducial Markers. [PDF]
Madeira T, Oliveira M, Dias P.
europepmc +1 more source

