Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer +17 more
wiley +1 more source
Lossless Compression of Large Field-of-View Infrared Video Based on Transform Domain Hybrid Prediction. [PDF]
Liu Y, Zhang R, Zhang Y, Chen Y.
europepmc +1 more source
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho +13 more
wiley +1 more source
Chinese small and medium-sized city image communication on Douyin: Algorithmic heuristics and cultural resilience in short-video ecologies. [PDF]
Li F, Peng X.
europepmc +1 more source
Magnetic Water Cleaning of Estrogens via Tight yet Dynamic Binding to Nanoparticles
Micropollution is one of the big challenges humanity faces with estrogen hormones being emerging pollutants of concern. Here, a supramolecular design strategy is presented that generates a simple nano‐adsorbent material to magnetically remove low‐concentrated estrogens from water.
Lukas Müller +25 more
wiley +1 more source
Fast 3D dynamic visualization of porcine spermatozoa by using high-resolution wavefront coding light sheet microscopy and machine learning. [PDF]
Licea-Rodriguez J +8 more
europepmc +1 more source
Low‐dose electron holography is limited by shot noise, which buries weak phase signals. HoloDenoiser, a physics‐informed network that works simultaneously in the spatial and frequency domains, locates and protects the holographic sideband while suppressing noise in the hologram.
Ye Luo +10 more
wiley +1 more source
Rise and subsequent fall in neuro-behavioral coupling during learning a skilled reaching task is revealed by generative AI. [PDF]
Tanabe S +5 more
europepmc +1 more source
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li +8 more
wiley +1 more source
FlowRoI: fast optical-flow-based Roi extraction for high-throughput immune cell image compression. [PDF]
Xu X +7 more
europepmc +1 more source

