Results 61 to 70 of about 608,944 (344)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

White light emitting diode correlated colour temperature influence on image analysis in Sala mango quality assessment

open access: yesJournal of Spectral Imaging, 2018
Colour analysis is one of the common techniques used in assessing fruits quality, especially for types of fruit that have a natural transformation in peel colour according to the stage of maturity and ripening.
Wan Long Chiong   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Image processing for smart browsing of ocean colour data products and subsequent incorporation into a multi-modal sensing framework [PDF]

open access: yes, 2010
Ocean colour is defined as the water hue due to the presence of tiny plants containing the pigment chlorophyll, sediments and coloured dissolved organic material and so water colour can provide valuable information on coastal ecosystems.
Diamond, Dermot   +5 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A novel colour image encryption based on fractional order Lorenz system

open access: yesSystems Science & Control Engineering, 2021
A colour image encryption algorithm based on fractional Lorenz system has been developed in this paper. Firstly, the colour image has been divided into three layers: R, G, and B, and Arnold map has been used for scrambling the three layers separately ...
Shixu Li   +3 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Concept of Computer-Aided Assessment of the Technical Condition of Operated Gas Turbine Vanes

open access: yesPolish Maritime Research, 2018
The article presents a multi-stage algorithm for automatic (without any human, user – diagnostician intervention) detection of vanes-blades (technical objects) and their surfaces on a digital image, combined with color analysis, aimed at determining the ...
Bogdan Mariusz   +2 more
doaj   +1 more source

Design and validation of tailored colour reference charts for monitoring cultural heritage degradation

open access: yesHeritage Science, 2021
Colour changes of cultural heritage objects can be related with degradation of materials, thus a proper colour monitoring system can be used to detect conservation problems.
Blanca Ramírez Barat   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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