Results 161 to 170 of about 11,782,843 (259)

Long‐Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair

open access: yesAdvanced Science, EarlyView.
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing   +9 more
wiley   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

open access: yesAdvanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler   +4 more
wiley   +1 more source

XChrom: A Cross‐Cell Chromatin Accessibility Prediction Model Integrating Genomic Sequence and Cellular Context

open access: yesAdvanced Science, EarlyView.
XChrom is a deep learning framework that integrates genomic sequence and single‐cell context to predict chromatin accessibility. It generalizes to unseen cells and genomic regions, enabling cross‐sample and cross‐species analysis. Applied to COVID‐19 patient data, XChrom reveals key transcriptional regulatory mechanisms and disease‐associated ...
Yuanyuan Miao   +5 more
wiley   +1 more source

Neutron Depth Profiling: The Core Link Connecting the Microscopic Mechanisms of Lithium‐Ion Batteries With Intelligent Design

open access: yesAdvanced Science, EarlyView.
Neutron depth profiling exploits the 6Li(n,3H)4He reaction to provide quantitative, isotope‐specific, depth‐resolved maps of lithium inside operating lithium‐ion batteries, directly linking lithium transport, dendrite growth and interfacial short‐circuiting to a physics‐informed machine‐learning roadmap that turns this non‐destructive operando ...
Yulong Zhang   +8 more
wiley   +1 more source

Accelerating High‐Fidelity Airfoil Design via Physics‐Informed Video Diffusion Model

open access: yesAdvanced Science, EarlyView.
Physics‐informed video diffusion enables rapid inverse aerodynamic design by mapping target lift‐to‐drag response to airfoil geometries and full‐field flow distributions. Trained on 53 400 DNS samples, the model achieves over 90% fidelity with ∼30 s inference, while experimentally realized propeller designs demonstrate a practical pathway from ...
Yifeng Ai   +9 more
wiley   +1 more source

Mechanically‐Gated Stochastic Resonance for All‐Optical Acoustic Sensing in Noisy Environments

open access: yesAdvanced Science, EarlyView.
A mechanically‐gated stochastic resonance (MGSR) sensing system is demonstrated, wherein stochastic resonance is enabled by an all‐optical bistable fiber Bragg grating feedback loop and gated by mechanical resonance. Under ambient noise, the system generates bistable outputs satisfying the Kramers escape‐rate condition, yielding signal‐to‐noise ratio ...
Xuyu Zhang   +9 more
wiley   +1 more source

Image denoising by adaptive lifting schemes

open access: yes, 2010
Image denoising by adaptive lifting ...
Abid, Manel   +2 more
core  

Emerging Memory and Device Technologies for Hardware‐Accelerated Model Training and Inference

open access: yesAdvanced Electronic Materials, EarlyView.
This review investigates the suitability of various emerging memory technologies as compute‐in‐memory hardware for artificial intelligence (AI) applications. Distinct requirements for training‐ and inference‐centric computing are discussed, spanning device physics, materials, and system integration.
Yoonho Cho   +6 more
wiley   +1 more source

From Top to Bottom: Manufacturing Process‐Context Aware Resolution of Energy Device Electrodes Through a 3D Diffusion Generative Model

open access: yesAdvanced Energy Materials, EarlyView.
The application of a generative diffusion model, enhanced with a training data augmentation pipeline retaining the manufacturing process context of electrode microstructures, leads to improved fidelity of the through‐plane tortuosity factor in the AI generated samples.
Victor Ramirez‐Camacho   +5 more
wiley   +1 more source

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