Results 101 to 110 of about 11,518,650 (280)
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Study of the Tourism Destination Image Formation Process and the Factors Affecting It [PDF]
Muṭāli̒āt-i Mudīriyyat-i Gardishgarī, 2010 Tourism Destination Image (TDI) has an essential role and impact on the tourist' decision making process, destination selection and the tourists behavior.
abolfazl taj zadeh namin +1 more
doaj
, 2017 Abstract from the presentation of: City destination image - How destination characteristics can be interconnected with visitors' destination image Göran Andersson & Saeid Abbasian Tourism Studies, Södertörn University, Sweden Email: goran.andersson@sh.se Destination Management Organisations (DMO) package the city image into a clear brand in ...
Andersson, Göran, Abbasian, Saeid
openaire +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Frontiers in Sustainable TourismDigital transformation is reshaping tourism markets by enabling destinations to communicate with prospective visitors, strengthen their online reputation, and present distinctive destination experiences through digitally connected environments.
Dawood, Sirab Ali, Tao Hu, He Biao
doaj +1 more source
The Effect of Country Based Image in Accurance of Brand in Cultural Destinations [PDF]
PASOS Revista de Turismo y Patrimonio Cultural, 2010 Despite its location and historical and cultural attractions, Izmir has been unable to consistently achieve its tourism goals, as evidenced by fluctuating numbers in tourism earnings and a small share of the international tourism market. This discrepancy
Hulya Kurgun
doaj
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
, 2017 Destination image is widely used in marketing and branding tourist destinations as image plays an essential role in tourists’ destination choices. Travel attributes are considered the key factors in positioning successful destination images. However, not
Dabphet, Siripen
core +1 more source