Results 111 to 120 of about 1,074,043 (334)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Improving biomedical image quality with computers [PDF]

open access: yes
Computerized image enhancement techniques used on biomedical radiographs and ...
Selzer, R. H.
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

DEDU: Dual-Enhancing Dense-UNet for Lowlight Image Enhancement and Denoise

open access: yesIEEE Access
In this paper, we propose an innovative image enhancement algorithm called “Dual-Enhancing-Dense-UNet (DEDUNet)” that simultaneously performs image brightness enhancement and reduces noise.
Hyungjoo Park   +2 more
doaj   +1 more source

Speckle Reduction with Attenuation Compensation for Skin OCT Images Enhancement [PDF]

open access: yes
The enhancement of skin image in optical coherence tomography (OCT) imaging can help dermatologists to investigate tissue layers more accurately, hence the more efficient diagnosis.
Avanaki, Mohammad R. N.   +1 more
core  

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

A mine image enhancement method based on structural texture decomposition

open access: yesGong-kuang zidonghua
There is a phenomenon of low lighting and excessive dust in underground mines, which leads to uneven lighting, blurriness, and loss of details in the images captured by monitoring videos. It affects subsequent intelligent image recognition. Existing mine
ZHANG Hong, SUO Tingfeng, SONG Wanying
doaj   +1 more source

Home - About - Disclaimer - Privacy