Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Enhanced tumor detection in the presence of liver cirrhosis: Experimental study on the diagnostic value of a superparamagnetic iron oxide MR imaging contrast agent (NSR 0430) [PDF]
Rainald Bachmann+5 more
openalex +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Application of fuzzy reasoning for filtering and enhancement of ultrasonic images [PDF]
J. P. Sacha+4 more
openalex +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Enhanced visualisation of acute macular neuroretinopathy by spectral imaging [PDF]
Lone K. Tingsgaard+2 more
openalex +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
Gadolinium-Enhanced Magnetic Resonance Imaging of 36 Patients One Year After Lumbar Disc Resection
Tycho Tullberg, Per Grane, Johan Isacson
openalex +1 more source
Radiative effect of cirrus clouds in Meteosat Second Generation Spinning Enhanced Visible and Infrared Imager channels [PDF]
Matthias Wiegner+2 more
openalex +1 more source