Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Application of CycleGAN-based low-light image enhancement algorithm in foreign object detection on belt conveyors in underground mines. [PDF]
Zhao A, Zheng Q, Li L.
europepmc +1 more source
Pulse Sequence Optimization for MR Imaging of the Liver Enhanced with Superparantagnetic Iron Oxide
openalex +2 more sources
Expectation of Pain Enhances Responses to Nonpainful Somatosensory Stimulation in the Anterior Cingulate Cortex and Parietal Operculum/Posterior Insula: an Event-Related Functional Magnetic Resonance Imaging Study [PDF]
Nobukatsu Sawamoto+7 more
openalex +1 more source
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
Image enhancement network based on fiber topology-preserving multi-module fusion for neuron reconstruction. [PDF]
Chen W+7 more
europepmc +1 more source
Principles and Current Clinical Applications of Contrast-enhanced Magnetic Resonance Imaging
Akihiro Tanimoto
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
PCAFA-Net: A Physically Guided Network for Underwater Image Enhancement with Frequency-Spatial Attention. [PDF]
Cheng K+5 more
europepmc +1 more source
Detection of focal hepatic lesions: Comparison of unenhanced and SHU 555 A-enhanced MR imaging versus biphasic helical CTAP [PDF]
Ahmed Ba‐Ssalamah+9 more
openalex +1 more source