Results 251 to 260 of about 1,341,334 (344)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Optical Coherence Tomography Image Enhancement and Layer Detection Using Cycle-GAN. [PDF]

Diagnostics (Basel)
Kim YE, Lee EJ, Yoon JS, Kwak J, Kim H.
europepmc   +1 more source

Breast cancer in dense breast: Detection with contrast-enhanced dynamic MR imaging [PDF]

, 2000
Hiroko Kawashima, Osamu Matsui, Masayuki Suzuki, Masumi Kadoya, Mari Tawara, Akitaka Nonomura, Masakuni Noguchi, Tsutomu Takashima   +7 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Underwater image enhancement based on optimally weighted histogram framework and improved Fick's law algorithm. [PDF]

Sci Rep
Liu Y, Qiao Z, Ye Z, Zhou W, Wang M, He Q, Cai T.   +6 more
europepmc   +1 more source

Artificial neural network visual model for image quality enhancement [PDF]

, 2000
Sheng Chen, Z. He, P.M. Grant
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

UICE-MIRNet guided image enhancement for underwater object detection. [PDF]

Sci Rep
Sarkar P, De S, Gurung S, Dey P.
europepmc   +1 more source

387 Enhancement CT Imaging of Intra hepatic Portal vein and Hepatic Vein with Helical CT

, 1995
Noboru Higashimoto, Yasuhiro Nakazawa, Takahito Terada, Tohru Kojima, Takao Kuroha, Toshio Maeno   +5 more
openalex   +2 more sources

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

FEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev   +3 more
wiley   +1 more source