Results 31 to 40 of about 67,648 (245)
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Enhanced CNN for image denoising [PDF]
CAAI Transactions on Intelligence Technology, 2019 Owing to the flexible architectures of deep convolutional neural networks (CNNs) are successfully used for image denoising. However, they suffer from the following drawbacks: (i) deep network architecture is very difficult to train. (ii) Deeper networks face the challenge of performance saturation.
Lunke Fei +5 more
openaire +3 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Learned perceptual image enhancement [PDF]
2018 IEEE International Conference on Computational Photography (ICCP), 2018 Learning a typical image enhancement pipeline involves minimization of a loss function between enhanced and reference images. While L1 and L2 losses are perhaps the most widely used functions for this purpose, they do not necessarily lead to perceptually compelling results.
Hossein Talebi, Peyman Milanfar
openaire +2 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Image-Enhanced Endoscopy in Practice [PDF]
Canadian Journal of Gastroenterology, 2009 The detection, diagnosis and treatment of early cancers offers the best hope for the prevention and cure of gastrointestinal cancers – one of the leading causes of death worldwide (1). The detection of pre- or early cancer using white light endoscopy can be challenging because their morphology can be inconspicuous (ie, nonpolypoid; slightly elevated ...
Roy Soetikno +2 more
openaire +4 more sources
FEBS Letters, EarlyView.The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley +2 more
wiley +1 more source
Choosing the Optimal Spatial Domain Measure of Enhancement for Mammogram Images
International Journal of Biomedical Imaging, 2014 Medical imaging systems often require image enhancement, such as improving the image contrast, to provide medical professionals with the best visual image quality. This helps in anomaly detection and diagnosis.
Karen Panetta, Arash Samani, Sos Agaian
doaj +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Integral invariants for image enhancement [PDF]
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2013 Medical images pose a major challenge for image analysis: often they have poor signal-to-noise, necessitating smoothing; yet such smoothing needs to preserve the boundaries of regions of interest and small features such as mammogram microcalcifications.
Janan, Faraz, Brady, Michael
openaire +4 more sources