Results 51 to 60 of about 424,065 (302)

Research on SSVEP‐EEG feature enhancement algorithm based on fractional differentiation

open access: yesThe Journal of Engineering
Steady‐state visual evoked potentials (SSVEP), significant in brain‐computer interfaces (BCI) and medical diagnostics, benefit from enhanced signal processing for improved analysis and interpretation.
Zenghui Li   +5 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

DAF‐Retinex: Preserve the image detailed features and restore the reflected image

open access: yesIET Image Processing
Currently, deep learning methods for low‐light image enhancement tasks mainly focus on the illumination of images, while neglecting the problems of image noise and feature loss.
Shiyu Huang, Zijun Gao, Jue Wang, Bo Li
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Multi‐domain pseudo‐reference quality evaluation for infrared and visible image fusion

open access: yesIET Image Processing
Infrared and visible image fusion involves merging the advantages of infrared and visible images to generate a composite image that encompasses thermal radiation as well as intricate texture details.
Xiangchao Meng   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Contrast Enhancement of Microscopy Images Using Image Phase Information

open access: yesIEEE Access, 2018
Contrast enhancement is an important preprocessing step for the analysis of microscopy images. The main aim of contrast enhancement techniques is to increase the visibility of the cell structures and organelles by modifying the spatial characteristics of
Serdar Cakir   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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