Results 81 to 90 of about 12,352,701 (307)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A robust color enhancement for underwater images

open access: yesAlexandria Engineering Journal
Due to various complex factors in underwater environments. Several issues must to be considered in obtaining clear underwater images, including color cast, low contrast, blurry details, haze, climate, environment and human factors can significantly ...
Kuo-Jui Hu   +4 more
doaj   +1 more source

Contrast Enhancement of Microscopy Images Using Image Phase Information

open access: yesIEEE Access, 2018
Contrast enhancement is an important preprocessing step for the analysis of microscopy images. The main aim of contrast enhancement techniques is to increase the visibility of the cell structures and organelles by modifying the spatial characteristics of
Serdar Cakir   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

A Fast Single Image Haze Removal Algorithm Using Color Attenuation Prior [PDF]

open access: yes, 2015
Single image haze removal has been a challenging problem due to its ill-posed nature. In this paper, we propose a simple but powerful color attenuation prior for haze removal from a single input hazy image.
Zhu, Qingsong   +5 more
core   +1 more source

(a) Segment Image without Enhancement (Green lines indicates the missing Vessels (b) Segment Image with Enhancement.

open access: yes, 2023
(a) Segment Image without Enhancement (Green lines indicates the missing Vessels (b) Segment Image with Enhancement.
Hesham Abdushkour (16617908)   +8 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Nonlinear retinal image enhancement for vessel detection

open access: yes, 2017
Retinal vessel detection is an essential part of the computer-aided diagnosis of eye diseases. Due to non-perfect imaging environment, retinal images often appear with intensity variations and artificial noises.
Jiang, Xudong   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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