Results 81 to 90 of about 15,311,076 (365)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Pre‐trained low‐light image enhancement transformer

open access: yesIET Image Processing
Low‐light image enhancement is a longstanding challenge in low‐level vision, as images captured in low‐light conditions often suffer from significant aesthetic quality flaws.
Jingyao Zhang, Shijie Hao, Yuan Rao
doaj   +1 more source

Endoscopic image enhancement with noise suppression

open access: yesHealthcare Technology Letters, 2018
Stereoscopic endoscopes have been used increasingly in minimally invasive surgery to visualise the organ surface and manipulate various surgical tools. However, insufficient and irregular light sources become major challenges for endoscopic surgery.
Wenyao Xia   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

DCTE-LLIE: A Dual Color-and-Texture-Enhancement-Based Method for Low-Light Image Enhancement

open access: yesComputers
The enhancement of images captured under low-light conditions plays a vitally important role in the area of image processing and can significantly affect the performance of following operations.
Hua Wang   +3 more
doaj   +1 more source

Quality enhancement in image enlargement [PDF]

open access: yes, 1995
Interpolation methods, usually employed in image enlargement, cause a degradation of the image quality in proximity to the edges. In fact, the best interpolation leads to fuzziness effects often due to the image features ignored during the process. In order to have a contained definition loss after the enlargement operation, it is necessary to consider
MARINO, Francescomaria   +1 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Research on SSVEP‐EEG feature enhancement algorithm based on fractional differentiation

open access: yesThe Journal of Engineering
Steady‐state visual evoked potentials (SSVEP), significant in brain‐computer interfaces (BCI) and medical diagnostics, benefit from enhanced signal processing for improved analysis and interpretation.
Zenghui Li   +5 more
doaj   +1 more source

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