Results 211 to 220 of about 5,936 (296)

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu   +5 more
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Ferroptosis and Its Emerging Role in Gestational Diabetes Mellitus

open access: yesMedicine Advances, EarlyView.
Ferroptosis contributes to the development of gestational diabetes mellitus (GDM) through iron overload, lipid peroxidation, and antioxidant system disruption. These changes impair adipocyte and β‐cell function, promoting insulin resistance and hyperglycemia.
Jinfeng Xu   +4 more
wiley   +1 more source

Computing Bonds Between Formal Contexts

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT The notion of bond was introduced as a technique to aggregate information from multiple datasets without modifying the information already present in each of the datasets. This notion has been extended to several fuzzy frameworks, including the residuated lattice setting, which we also consider in this paper.
Roberto G. Aragón   +2 more
wiley   +1 more source

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