Results 121 to 130 of about 11,447,895 (308)

Managing intraoperative fatigue failure of proximal jig for interlocking nail – A case report and technical tip

open access: yesJournal of Orthopaedic Diseases and Traumatology, 2019
Interlocking nails are widely used implants in the management of long-bone diaphyseal fractures. Interlocking nailing is an easy, predictable, and standard method owing to the presence of ancillary instruments and image intensifier. Proximal jigs help in
Binit Singh   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Multiple-exposure image-intensifier camera. [For photography of detonations]

open access: yes, 1976
An image-intensifier camera with light gain of a few thousand times and exposure pulse times as short as 8 ns has been applied to the study of high explosives.
Chiles, W. C.   +2 more
core  

An image intensifier-scintillator device for determination of profiles and images of weak beams of ionizing particles or X-rays [PDF]

open access: yes, 1961
An instrument for determining the shape and intensity distribution of particle and X-ray beams has been developed using an image intensifier tube together with a bundle of filaments of scintillator.
Jones, Lawrence W., Perl, Martin L.
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Concept for Image Intensifier with CMOS Imager Output Interface

open access: yes, 2008
A concept is described for the detection and location of transient objects, in which a “pixel-binary ” CMOS imager is used to give a very high effective frame rate for the imager.
Paul J. Thomas   +3 more
core  

Schematic representation of theTRICLOBS sensor suite layout.

open access: yes, 2016
The long-wave part of the incoming radiation is reflected into an uncooled infrared microbolometer by a LWIR (hot) mirror, the near-infrared part is reflected by a dichroic beam splitter (NIR mirror) towards an image intensifier (ICU), while the visual ...
Alexander Toet (481620)   +2 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

X-RAY IMAGE INTENSIFIER FOR NONDESTRUCTIVE TESTING

open access: yes, 1997
提出一种用于工业射线检测的新型X射线图象增强器及其实时成象系统,并给出它们的结构和性能。A new X-ray image intensiFier and a real-time imaging system are put Forward For industrial X-ray nondestructive testing and their structures and perFormances are also ...
林振旺, 杨晓文, 何秀堂
core  

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