Results 131 to 140 of about 65,660 (274)

Intelligent laser scanning for computer aided manufacture. [PDF]

, 2006
Reverse engineering requires the acquisition of large amounts of data describing the surface of an object, sufficient to replicate that object accurately using appropriate fabrication techniques.
Denby, Alistair John, Denby, AJ
core  

Artificial intelligence-based detection of dens invaginatus in panoramic radiographs

BMC Oral Health
Objective The aim of this study was to automatically detect teeth with dens invaginatus (DI) in panoramic radiographs using deep learning algorithms and to compare the success of the algorithms.
Ayse Hanne Sarı, Hasan Sarı, Guldane Magat   +2 more
doaj   +1 more source

Improving lithological mapping by support vector machine classification using integrated visible-near infrared, shortwave infrared, and thermal infrared of ASTER data sets

Geocarto International
This study aims to enhance lithological mapping by employing Support Vector Machine (SVM) classification on integrated visible-near infrared (VNIR)-shortwave infrared (SWIR), and thermal infrared (TIR) datasets from the Advanced Spaceborne Thermal ...
Mahdieh Hosseinjanizadeh, Hassanzadeh Reza, Mehdi Honarmand   +2 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Deep learning–assisted biodiversity assessment in deep-sea benthic megafauna communities: a case study in the context of polymetallic nodule mining

Frontiers in Marine Science
IntroductionTechnological developments have facilitated the collection of large amounts of imagery from isolated deep-sea ecosystems such as abyssal nodule fields.
Daphne Cuvelier, Martin Zurowietz, Tim W. Nattkemper   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A conceptual approach to the early learning of Algebra using a computer [PDF]

This thesis describes an investigation into the conceptual understanding of algebra by early learners (age 11-13 years) and how a computer-based approach may be used to improve such, without any consequent loss of manipulative skills.
Thomas, Michael O. J.
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