Results 141 to 150 of about 13,295,115 (295)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Foundation Models Meet Medical Image Interpretation. [PDF]

Research (Wash D C)
Jiao L, Hao J, Li R, Li L, Liu X, Liu F, Ma W, Chen P, Huang Z, Yang J, Zhao J, Sun Q.   +11 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Navigating Challenges in Teleradiology Implementation: A Case Study from Saudi Arabia’s Healthcare System

Journal of Multidisciplinary Healthcare
Haitham Alahmad,1,* Mansour A Almanaa,1,* Ahmad Abanomy,1 Mohammad Alarifi,1 Khaled Alenazi,1 Mousa Matabi,2 Raed Albathi,3 Rayan Moslem4 1Department of Radiological Sciences, College of Applied Medical Sciences, King Saud University, Riyadh ...
Alahmad H, Almanaa MA, Abanomy A, Alarifi M, Alenazi K, Matabi M, Albathi R, Moslem R   +7 more
doaj  

Multimodal Large Language Models for Dental Chart Image Interpretation: Cross-Sectional Benchmarking Study With Students and Clinicians. [PDF]

JMIR Med Educ
Cho AY, Eo SH, Jeon MJ, Kim JH, Ihm J, Seo DG.   +5 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

An Autonomous SAR Image Interpretation Algorithm Based on Multi-Agent Collaborative Scheduling. [PDF]

Sensors (Basel)
Lu D, Zhang M, Guo Y, Li H, Liu N.
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Deep learning for fluorescence confocal microscopy image interpretation in radical prostatectomy. [PDF]

BJU Int
Fang L, Mayor N, Light A, Silvanto A, Haider A, Ng C, Gopalakrishnan A, Boaz RJ, Tanaka MB, Khoubehi B, Hellawell G, Almeida-Magana R, Mendes L, Dinneen E, Shaw G, Challacombe B, Cathcart P, Connor MJ, Shah TT, Ahmed HU, Fiorentino F, Giannarou S, Winkler M.   +22 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source