Results 71 to 80 of about 11,907,247 (288)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
This thesis describes a lossy image compression algorithm. The algorithm provides a compression ratio that, on average, lies between the lossless PNG algorithm and the lossy JPEG algorithm.
Miremadi, Milaud
core +2 more sources
Image quality in lossy compressed digital mammograms [PDF]
Signal Processing, 1997 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Perlmutter, S. M. +13 more
openaire +4 more sources
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Influence of the Lossy Compression JPEG2000 standard on the Deformation of PSF
Acta Polytechnica, 2011 This paper deals with the influence of lossy compression algorithms on the deformation of the point spread function (PSF) of imaging systems in astronomy.
P. Páta
doaj
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Lossy Image Compression with Stochastic Quantization
Кібернетика та комп'ютерні технологіїIntroduction. Lossy image compression algorithms play a crucial role in various domains, including graphics, and image processing. As image information density increases, so do the resources required for processing and transmission.
Anton Kozyriev, Vladimir Norkin
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Metrics for Stereoscopic Image Compression [PDF]
, 2012 Metrics for automatically predicting the compression settings for stereoscopic images, to minimize file size, while still maintaining an acceptable level of image quality are investigated.
GORLEY, PAUL,WARD, Gorley, Paul Ward
core