Results 161 to 170 of about 376,443 (285)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Clinical application research of navigation system-assisted vertebroplasty for the treatment of lumbar osteoporotic compression fractures. [PDF]

BMC Surg
Lian Y, Xie Y, Yu H, Xuan A, Wei Y, Wang Z, Xiang L, Gu H.   +7 more
europepmc   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Artificial Intelligence in Intraoperative Imaging and Navigation for Spine Surgery: A Narrative Review. [PDF]

J Clin Med
Girgis M, Kelliher A, Pheasant MS, Tang A, Badve S, Chen T.   +5 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Ultrafast visual perception beyond human capabilities enabled by motion analysis using synaptic transistors. [PDF]

Nat Commun
Wang S, Zhao J, Pu T, Zhao L, Guo X, Cheng Y, Li C, Ma W, Tang C, Xu Z, Wang N, Occhipinti LG, Nathan A, Dahiya R, Wu H, Tao L, Gao S.   +16 more
europepmc   +1 more source

[Computer-assisted analysis of the activity of peroxidases of segmented-nucleus neutrophils using digital image processing].

Klinicheskaia laboratornaia diagnostika, 1994
Suggests a quantitative cytochemical method for assessment of neutrophilic peroxidase activity in patients with acute infarction using IBAS-2000 computer (Germany). The method holds good promise in assessment of the condition severity and prediction of its outcome and course.
openaire   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta-analysis of a confusion matrix. [PDF]

Oncol Lett
Hu Y, Liao W, Er Y, Tao Q.
europepmc   +1 more source

Image processing in medicine advances for phenotype characterization, computer-assisted diagnosis and surgical planning

, 2011
En esta Tesis presentamos nuestras contribuciones al estado del arte en procesamiento digital de imágenes médicas, articulando nuestra exposición en torno a los tres principales objetivos de la adquisición de imágenes en medicina: la prevención, el diagnóstico y el tratamiento de las enfermedades.
openaire   +2 more sources