Results 161 to 170 of about 16,653,457 (281)

BAGLS-VF: a comprehensive dataset for glottal area and vocal fold segmentations. [PDF]

BMC Res Notes
Razi S, Kist AM.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

AlveolEye: rapid and precise lung morphometry guided by computer vision. [PDF]

Am J Physiol Lung Cell Mol Physiol
Hirsh J, Hirsh S, Shirazi SP, Hirsh J, Douglas I, Garg S, Son Y, Pierre-Louis A, Bunn C, Jetter CS, James TJ, Sharkey AL, Benjamin JT, Gokey JJ, Ochi A, Reese J, Renfree MB, Shaw G, Kropski JA, Sucre JMS, Negretti NM.   +20 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Automation, Robotics, and Artificial Intelligence in Seafood Processing: Advancements, Challenges, and Future Prospects. [PDF]

J Food Sci
Yadav KK, Sharma S, Mehta NK, Bansal N, Mohanty S, Bhalavey P, Kulshrestha T, Singh A.   +7 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Laser scanning registration for knee arthroplasty. [PDF]

Bone Joint Res
Warren T, Hayter Otaola U, Robertson B, Khan R, Withers S, Goonatillake H, Hewitt B, Kozak T, Kuriakose S, Batanony T, Greenwald J, Meftah M.   +11 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Computer Vision-Assisted Semiautomatic Analysis of Zooplankton in a Longitudinal Study of the Ecological State of Lake Baikal. [PDF]

Biology (Basel)
Rusanovskaya OO, Oreshkov SS, Demidova AA, Rzhepka TP, Silow EA, Shadrin NV, Shimaraeva SV, Timofeyev MA.   +7 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source