Results 51 to 60 of about 841,129 (301)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

True color night vision correlated imaging based on intensity correlation of light [PDF]

arXiv, 2021
Night vision imaging is a technology that converts non-visible object to human eyes into visible image in night and other low light environments. However, the conventional night vision imaging can only directly produce grayscale image. Here, we propose a novel night vision imaging method based on intensity correlation of light. The object's information
arxiv  

Reply to: “Definition of SPSS: we need to speak the same language” [PDF]

Journal of Hepatology, 2020
In response to Nicoara-Farcau and colleagues, we agree that gastrorenal shunts, seem important, since they are found in many patients with gastric varices and herefore possibly associate with bleeding. In total, 990 SPSS in patients with available follow up data were found. The distribution of the types of SPSS is shown.
Antoni Perez-Poch, Francisco Alpiste, Michael Praktiknjo, Joan Genescà, Cristina de la Torre, Inés del Val, Jordi Torner, Macarena Simón-Talero, Jonel Trebicka, Jonel Trebicka, Wenyi Gu   +10 more
openaire   +5 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

An effective and open source interactive 3D medical image segmentation solution

Scientific Reports
3D medical image segmentation is a key step in numerous clinical applications. Even though many automatic segmentation solutions have been proposed, it is arguably that medical image segmentation is more of a preference than a reference as inter- and ...
Yi Gao, Xiaohui Chen, Qinzhu Yang, Andras Lasso, Ivan Kolesov, Steve Pieper, Ron Kikinis, Allen Tannenbaum, Liangjia Zhu   +8 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Compresión de imágenes médicas

Biomédica: revista del Instituto Nacional de Salud, 2013
La medicina moderna es una actividad cada vez más compleja, basada en la información proveniente de múltiples fuentes: historias clínicas, dictáfonos e imágenes y vídeos provenientes de múltiples dispositivos.
Tatiana Noreña, Eduardo Romero
doaj   +1 more source

Towards a standardized framework for AI-assisted, image-based monitoring of nocturnal insects

Philosophical Transactions of the Royal Society of London. Biological Sciences
Automated sensors have potential to standardize and expand the monitoring of insects across the globe. As one of the most scalable and fastest developing sensor technologies, we describe a framework for automated, image-based monitoring of nocturnal ...
D. Roy, J. Alison, T. August, M. Bélisle, K. Bjerge, J. J. Bowden, M. Bunsen, F. Cunha, Q. Geissmann, K. Goldmann, A. Gomez-Segura, A. Jain, C. Huijbers, M. Larrivée, J. L. Lawson, H. M. Mann, M. Mazerolle, K. P. McFarland, L. Pasi, S. Peters, N. Pinoy, D. Rolnick, G. Skinner, O. T. Strickson, A. Svenning, S. Teagle, T. Høye   +26 more
semanticscholar   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source