Results 31 to 40 of about 847,754 (261)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A Two-Stage Attribute-Constraint Network for Video-Based Person Re-Identification
Person re-identification has gradually become a popular research topic in many fields such as security, criminal investigation, and video analysis. This paper aims to learn a discriminative and robust spatial–temporal representation for video ...
Wanru Song +4 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Selective focus saliency model driven by object class‐awareness
Current many salient object detection (SOD) models only focus on highlighting visual conspicuous region but fail to make saliency detection for specific targets. In this paper, a selective focus saliency model driven by object class‐awareness (SF‐OCA) to
Danpei Zhao +3 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Feature Encoder Guided Generative Adversarial Network for Face Photo-Sketch Synthesis
Face photo-sketch synthesis often suffers from many problems, such as low clarity, facial distortion, contents loss, texture missing and color inconsistency in the synthesized images.
Jieying Zheng +4 more
doaj +1 more source
Background Soil organic carbon (SOC) affects essential biological, biochemical, and physical soil functions such as nutrient cycling, water retention, water distribution, and soil structure stability.
Johanna Elizabeth Ayala Izurieta +7 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Revamped fly‐over for accurate colon visualisation in virtual colonoscopy
This study revisits a visualisation technique for virtual colonoscopy, known as virtual fly‐over (FO). The method views the entire colon anatomy from above the centreline.
Marwa Ismail +7 more
doaj +1 more source

