Results 51 to 60 of about 847,754 (261)

Region Based CNN for Foreign Object Debris Detection on Airfield Pavement

open access: yesSensors, 2018
In this paper, a novel algorithm based on convolutional neural network (CNN) is proposed to detect foreign object debris (FOD) based on optical imaging sensors.
Xiaoguang Cao   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Optical classification of images at different wavelengths using spectral diffractive neural networks

open access: yesКомпьютерная оптика
A solution of several different problems of image classification at several different wavelengths using a diffractive neural network (DNN) consisting of sequentially located phase diffractive optical elements (DOEs) is considered.
G.A. Motz   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Gradient method for designing cascaded DOEs focusing radiation of different wavelengths

open access: yesКомпьютерная оптика
The design of cascaded diffractive optical elements (DOEs) generating several specified intensity distributions for several incident beams with different wavelengths is considered.
G.A. Motz   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Near-Infrared Band Synthesis From Earth Observation Imagery With Learned Location Embeddings and Task-Driven Loss Functions

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The acquisition of near-infrared (NIR) imagery is crucial for various remote sensing (RS) applications but is often unavailable in RS datasets, providing only the red–green–blue (RGB) bands.
Simon Donike   +3 more
doaj   +1 more source

Airport Detection Using End-to-End Convolutional Neural Network with Hard Example Mining

open access: yesRemote Sensing, 2017
Deep convolutional neural network (CNN) achieves outstanding performance in the field of target detection. As one of the most typical targets in remote sensing images (RSIs), airport has attracted increasing attention in recent years.
Bowen Cai   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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