Results 91 to 100 of about 375,552 (309)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Automatic Apparent Nasal Index from Single Facial Photographs Using a Lightweight Deep Learning Pipeline: A Pilot Study

Medicina
Background and Objectives: Quantifying nasal proportions is central to facial plastic and reconstructive surgery, yet manual measurements are time-consuming and variable.
Babak Saravi, Lara Schorn, Julian Lommen, Max Wilkat, Andreas Vollmer, Hamza Eren Güzel, Michael Vollmer, Felix Schrader, Christoph K. Sproll, Norbert R. Kübler, Daman D. Singh   +10 more
doaj   +1 more source

Digital mammography, cancer screening: Factors important for image compression [PDF]

The use of digital mammography for breast cancer screening poses several novel problems such as development of digital sensors, computer assisted diagnosis (CAD) methods for image noise suppression, enhancement, and pattern recognition, compression ...
Blaine, G. James, Brown, G. Stephen, Clarke, Laurence P., Doi, Kunio, Kallergi, Maria, Shtern, Faina, Winfield, Daniel L., Yaffe, Martin J.   +7 more
core   +1 more source

Proceedings of the Third Computing Women Congress (CWC 2008): Student papers [PDF]

, 2008
The Third Computing Women Congress was held at the University of Waikato, Hamilton, New Zealand from February 11th to 13th, 2008. The Computing Women Congress (CWC) is a Summer University for women in Computer Science.
Hempstalk, Kathryn, Hinze, Annika, Schweer, Andrea   +2 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Removing defocused objects from single focal plane scans of cytological slides

Journal of Pathology Informatics, 2016
Background: Virtual microscopy and automated processing of cytological slides are more challenging compared to histological slides. Since cytological slides exhibit a three-dimensional surface and the required microscope objectives with high resolution ...
David Friedrich, Alfred Böcking, Dietrich Meyer-Ebrecht, Dorit Merhof   +3 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

CIE L*a*b*: comparison of digital images obtained photographically by manual and automatic modes

Brazilian Oral Research, 2012
The aim of this study was to analyze the color alterations performed by the CIE L*a*b* system in the digital imaging of shade guide tabs, which were obtained photographically according to the automatic and manual modes.
Fabiana Takatsui, Marcelo Ferrarezi de Andrade, Maximiliano Piero Neisser, Luiz Antônio Borelli Barros, Leonor de Castro Monteiro Loffredo   +4 more
doaj  

The computer treatment of remotely sensed data: An introduction to techniques which have geologic applications [PDF]

Several aspects of computer-assisted analysis techniques for image enhancement and thematic classification by which LANDSAT MSS imagery may be treated quantitatively are explained.
Parada, N. D. J., Paradella, W. R., Vitorello, I.   +2 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source