Results 141 to 150 of about 473,139 (306)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Learning based Image Quality Assessment [PDF]

open access: yes, 2015
In this thesis, we present an abstract view of image quality assessment algorithms. Most of the research in the area of image quality assessment is focused on the scenario where the end-user is a human observer and therefore commonly known as ...
Koduri, Manasa Priya
core  

Objective quality estimation for digital images and video streams

open access: yes, 2022
S.71-87In the context of multimedia and hypermedia systems, the aspects of image quality are gaining increasingly in importance. Two tasks have to be fulfilled.
Gerfelder, N., Müller, W.
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Blind image and video quality assessment using natural scene and motion models

open access: yes, 2013
textWe tackle the problems of no-reference/blind image and video quality evaluation. The approach we take is that of modeling the statistical characteristics of natural images and videos, and utilizing deviations from those natural statistics as ...
Saad, Michele Antoine
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

An image quality assessment metric based contourlet

open access: yes, 2008
In reduced-reference (RR) image quality assessment (IQA), the visual quality of distorted images is evaluated with only partial information extracted from original images.
Lu, W.   +11 more
core   +1 more source

TIQA-MRI: Toolbox for Perceptual Image Quality Assessment of Magnetic Resonance Images

open access: yesSoftwareX
Magnetic Resonance Imaging (MRI) plays a pivotal role in medical diagnostics and research as a non-invasive imaging tool. The accuracy and reliability of clinical evaluations depend heavily on the quality of MRI images, making high-quality imaging ...
Igor Stępień
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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