Results 71 to 80 of about 452,773 (262)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Fusion of Measures for Image Segmentation Evaluation

International Journal of Computational Intelligence Systems, 2019
Image segmentation is an important task in image processing. However, no universally accepted quality scheme exists for evaluating the performance of various segmentation algorithms or just different parameterizations of the same algorithm. In this paper,
Macmillan Simfukwe, Bo Peng, Tianrui Li
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Radiographic Image Quality in Referral Hospitals, Sari, Iran 2017

Journal of Mazandaran University of Medical Sciences, 2017
Background and purpose: Image quality together with low patient dose is two important goals in radiography procedures. Acquire radiographic images with inadequate quality give rise to uselessly patient dose, improper diagnosis, waste the cost and impose ...
Gholamreza Fallah Mohammadi, Ali Mohammadi, Aida Alizamani, Nastaran Kiumarsi, Hossein Shemirani   +4 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

ANALYSIS AND PREDICTION OF FILTERING EFFICIENCY USING NO-REFERENCE IMAGE VISUAL QUALITY METRICS

Радіоелектронні і комп'ютерні системи, 2018
Images are subject to noise during acquisition, transmission and processing. Image denoising is highly desirable, not only to provide better visual quality, but also to improve performance of the subsequent operations such as compression, segmentation ...
Андрей Сергеевич Рубель, Владимир Васильевич Лукин   +1 more
doaj   +1 more source

Image quality evaluation: evaluation of the image quality of actual images by using machine learning models

Bulletin of Electrical Engineering and Informatics
Evaluating image features is a significant step in image processing in applications like number plate detection, vehicle tracking and many image processing-based applications. Image processing-based applications need accurate parts to get the best outcomes. Feature detection is done based on various feature detection techniques.
Shiva Shankar Reddy, Veeranki V. R. Maheswara Rao, Kalidindi Sravani, Silpa Nrusimhadri   +3 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source