Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Generic object recognition by combining distinct features in machine learning
, 2005 In a genetic image object recognition or categorization system, the relevant features or descriptors from a characteristic point, patch or region of an image are often obtained by different approaches. And these features are often separately selected and
Meng, Hongying +3 more
core
Fine-Grained Image Recognition with Bio-Inspired Gradient-Aware Attention. [PDF]
Biomimetics (Basel)Ma B +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
, 2012 Image feature extraction is a fundamental area of image processing and computer vision. There are many ways that techniques can be created that extract features and particularly novel techniques can be developed by taking influence from the physical ...
Cummings, Alastair
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Aphid-ResNetSwin: An Image Recognition Method with Improved Attention Mechanism for Graded Identification of <i>Myzus persicae</i>. [PDF]
InsectsLuo J +5 more
europepmc +1 more source
Imaging, Vision, and Pattern Recognition [PDF]
Applied Computational Intelligence and Soft Computing, 2018 Mourad Zaied +4 more
openaire +3 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Investigation of Flow Characteristics in a Stirred-Tank Bioreactor with Flexible Blades via Integrated PIV and Image Recognition. [PDF]
Bioengineering (Basel)Xu W, Cai C, Li Z, Lu H, Yang C, Liu B.
europepmc +1 more source