Results 51 to 60 of about 1,074,783 (331)

CCT4 promotes tunneling nanotube formation

open access: yesFEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto   +3 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Domain Transform Network for Photoacoustic Tomography from Limited-view and Sparsely Sampled Data

open access: yesPhotoacoustics, 2020
Medical image reconstruction methods based on deep learning have recently demonstrated powerful performance in photoacoustic tomography (PAT) from limited-view and sparse data.
Tong Tong   +7 more
doaj   +1 more source

On global randomized block Kaczmarz method for image reconstruction

open access: yesElectronic Research Archive, 2022
Image reconstruction represents an important technique applied in various fields such as medicine, biology, materials science, nondestructive testing, and so forth.
Ranran Li, Hao Liu
doaj   +1 more source

Quantum-implemented selective reconstruction of high-resolution images

open access: yes, 2004
This paper proposes quantum image reconstruction. Input-triggered selection of an image among many stored ones, and its reconstruction if the input is occluded or noisy, has been simulated by a computer program implementable in a real quantum-physical ...
Bischof, Horst   +3 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Single Image Super-Resolution Reconstruction with Preservation of Structure and Texture Details

open access: yesMathematics, 2023
In recent years, deep-learning-based single image super-resolution reconstruction has achieved good performance. However, most existing methods pursue a high peak signal-to-noise ratio (PSNR), while ignoring the quality of the structure and texture ...
Yafei Zhang   +4 more
doaj   +1 more source

SOWAT: Speckle Observations With Alleviated Turbulence

open access: yes, 2019
Adaptive optics (AO) systems and image reconstruction algorithms are indispensable tools when it comes to high-precision astrometry. In this paper, we analyze the potential of combining both techniques, i.e.
Bosco, Felix   +2 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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