Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
The impact of image resolution on power, bias, and confounding: A simulation study of ambient light at night exposure. [PDF]
Environ Epidemiol, 2021 McIsaac MA +4 more
europepmc +1 more source
Multiple Illumination Phaseless Super-Resolution (MIPS) with Applications To Phaseless DOA Estimation and Diffraction Imaging [PDF]
, 2017 Fariborz Salehi +2 more
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Reviewer #2 (Public Review): Deep Learning Using High-Resolution Images of Forearm Predicts Fracture
, 2023 Roland Chapurlat +9 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Do Radiographic Assessments of Periodontal Bone Loss Improve with Deep Learning Methods for Enhanced Image Resolution? [PDF]
Sensors (Basel), 2021 Moran M +4 more
europepmc +1 more source
, 2019 This chapter examines multiframe image super-resolution in a probabilistic framework. Many multiframe super-resolution algorithms begin by a point estimate of the unknown latent parameters, such as those describing the motion or the blur function. The focus of this chapter is on alternatives to this practice that can yield superior super-resolution ...
Pickup, L +3 more
openaire +1 more source
Development of Micro-Structured Fluorescent Plates for High-resolution Imaging [PDF]
, 2016 Takuro Sakai +3 more
openalex +1 more source
Change Detection Using Image Matching Techniques for High-Resolution Aerial Photographs
, 2023 Sung-jin Ma +3 more
openalex +1 more source