Results 61 to 70 of about 6,693,779 (355)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Image Retrieval Method Based on Local Diagonal Color Difference Descriptor [PDF]

open access: yesJisuanji gongcheng, 2016
For retrieval accuracy of Text-based Image Retrieval(TBIR) method is not high,this paper proposes a new image retrieval method.The hue and saturation components are reasonably quantified in HSV color space to make more detailed description for color ...
ZHANG Yubing,SONG Wei
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Metadata for Content-Based Image Retrieval

open access: yesStudia Universitatis Babes-Bolyai: Series Informatica, 2010
This paper presents an image retrieval technique that combines content based image retrieval with pre-computed metadata-based image retrieval. The resulting system will have the advantages of both approaches: the speed/efficiency of metadata-based image ...
Adrian Sterca, Daniela Miron
doaj  

Research of Image Retrieval Method Based on Improved Feature [PDF]

open access: yesXibei Gongye Daxue Xuebao, 2018
In the process of image retrieval, the traditional single feature can't reflect the distribution and details of image color and content, which have some adverse influence on the performance of image retrieval.

doaj   +1 more source

CAMP: Cross-Modal Adaptive Message Passing for Text-Image Retrieval [PDF]

open access: yesIEEE International Conference on Computer Vision, 2019
Text-image cross-modal retrieval is a challenging task in the field of language and vision. Most previous approaches independently embed images and sentences into a joint embedding space and compare their similarities. However, previous approaches rarely
Zihao Wang   +6 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

An Aquatic Organism Image Retrieval Hash Algorithm Based on DCT

open access: yesMATEC Web of Conferences, 2018
In order to overcome the disadvantages of traditional image retrieval algorithms such as inefficiency and time-consuming, an image retrieval algorithm based on DCT Hash is proposed.
Yu Yuanhui, Deng Ying, Lin Yanfen
doaj   +1 more source

A Novel Adaptive Feature Fusion Strategy for Image Retrieval

open access: yesEntropy, 2021
In the era of big data, it is challenging to efficiently retrieve the required images from the vast amount of data. Therefore, a content-based image retrieval system is an important research direction to address this problem. Furthermore, a multi-feature-
Xiaojun Lu   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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