Results 271 to 280 of about 6,403,045 (365)

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Visual Prostheses in the Era of Artificial Intelligence Technology. [PDF]

Eye Brain
Sarbout I, Gungor A, Ounissi M, Zaher S, Ptito M, Kupers R, Racoceanu D, Milea D.   +7 more
europepmc   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Computational modeling of visual salience alteration and its application to eye-movement data. [PDF]

Front Neurosci
Fujita Y, Murai T, Miyata J.
europepmc   +1 more source

Unanticipated Interfacial Redox Reaction in the NiOx Transport Layer of Perovskite Light‐Emitting Diodes

Advanced Science, EarlyView.
This study presents the unanticipated interfacial redox reaction between NiOx and perovskite, which is characterized by XPS. This redox reaction is one of the primary reasons for the bias‐induced instability of PeLEDs and is particularly suppressed by simply applying an interface layer between NiOx and perovskite.
Thi‐Hoai Do, Aswaghosh Loganathan, Yun‐Han Wu, Yaw‐Shyan Fu, Tzung‐Fang Guo   +4 more
wiley   +1 more source

Comparison of RETFound and a Supervised Convolutional Neural Network for Detection of Referable Glaucoma from Fundus Photographs. [PDF]

Ophthalmol Sci
Bolo K, Nguyen TH, Iyengar S, Li Z, Nguyen V, Wong BJ, Do JL, Ambite JL, Kesselman C, Daskivich LP, Xu BY.   +10 more
europepmc   +1 more source

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

The superficial layers of the primary visual cortex create a saliency map that feeds forward to the parietal cortex. [PDF]

PLoS Biol
Liu C, Liu C, Huber L, Zhaoping L, Zhang P.   +4 more
europepmc   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Explainable artificial intelligence (XAI) in medical imaging: a systematic review of techniques, applications, and challenges. [PDF]

BMC Med Imaging
Ahmed F, Naz NS, Khan S, Rehman AU, Ismael WM, Khan MA.   +5 more
europepmc   +1 more source