Results 131 to 140 of about 335,064 (318)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Contour evolution scheme for variational image segmentation and smoothing

, 2007
An algorithm, based on the Mumford–Shah (M–S) functional, for image contour segmentation and object smoothing in the presence of noise is proposed. However, in the proposed algorithm, contour length minimisation is not required and it is demonstrated ...
Sharif, Bayan, Mahmoodi, Sasan
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

A multiscale approach to texture-based image retrieval

, 2008
This paper presents research on a robust technique for texture-based image retrieval in multimedia museum collections. The aim is to be able to use a query image patch containing a single texture to retrieve images containing an area with similar texture
Fauzi, Mohammad Faizal Ahmad, Fauzi, Mohammad Faizal Ahmed, Lewis, Paul H.   +2 more
core   +1 more source

Soft Segmentation of Images

, 2019
Realistic editing of photographs requires careful treatment of color mixtures that commonly occur in natural scenes. These color mixtures are typically modeled using soft selection of objects or scene colors. Hence, accurate representation of these soft transitions between image regions is essential for high-quality image editing and compositing ...
openaire   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Markov mezők a képmodellezésben, alkalmazásuk az automatikus képszegmentálás területén = Markovian Image Models: Applications in Unsupervised Image Segmentation

, 2007
1) Kifejlesztettünk egy olyan szín és textúra alapú szegmentáló MRF algoritmust, amely alkalmas egy kép automatikus szegmentálását elvégezni. Az eredményeinket az Image and Vision Computing folyóiratban publikáltuk.
Kató, Zoltán
core  

Segment anything in medical images

Nature Communications
AbstractMedical image segmentation is a critical component in clinical practice, facilitating accurate diagnosis, treatment planning, and disease monitoring. However, existing methods, often tailored to specific modalities or disease types, lack generalizability across the diverse spectrum of medical image segmentation tasks.
Jun Ma, Yuting He, Feifei Li, Lin Han, Chenyu You, Bo Wang   +5 more
openaire   +4 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source