Results 91 to 100 of about 753,185 (297)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Instruments, 2017 The LinoSPAD camera system is a modular, compact and versatile time-resolved camera system, combining a linear 256 high fill factor pixel CMOS SPAD (single-photon avalanche diode) sensor with an FPGA (field-programmable gate array) and USB 3.0 ...
Samuel Burri +2 more
doaj +1 more source
Improving the geometric fidelity of imaging systems employing sensor arrays [PDF]
A sensor assembly to be carried on an aircraft or spacecraft which will travel along an arbitrary flight path, for providing an image of terrain over which the craft travels, is disclosed.
Jones, Kenneth L.
core +1 more source
A Software Retina for Egocentric & Robotic Vision Applications on Mobile Platforms [PDF]
, 2016 We present work in progress to develop a low-cost highly integrated camera sensor for egocentric and robotic vision. Our underlying approach is to address current limitations to image analysis by Deep Convolutional Neural Networks, such as the ...
Aragon Camarasa, Gerardo +5 more
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Accuracy of Shack-Hartmann wavefront sensor using a coherent wound fibre image bundle
, 2018 Shack-Hartmann wavefront sensors using wound fibre bundles are desired for multi-object adaptive optical systems to provide large multiplex positioned by Starbugs.
Goodwin, Michael +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A Review of Ion Implantation Technology for Image Sensors †
Sensors, 2018 Ion implantation technology is reviewed mainly from the viewpoint of image sensors, which play a significant role in implantation technology development.
Nobukazu Teranishi +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source