Results 221 to 230 of about 246,563 (312)

CMOS-Based Implantable Multi-Ion Image Sensor for Mg²⁺ Measurement in the Brain. [PDF]

Sensors (Basel)
Nakamura Y, Doi H, Kimura Y, Horio T, Choi YJ, Takahashi K, Noda T, Sawada K.   +7 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Study on 3D Effects on Small Time Delay Integration Image Sensor Pixels. [PDF]

Sensors (Basel)
Guo S, Zhou Q, Boulenc P, Klekachev AV, Wang X, Lahav A.   +5 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

A broadband hyperspectral image sensor with high spatio-temporal resolution. [PDF]

Nature
Bian L, Wang Z, Zhang Y, Li L, Zhang Y, Yang C, Fang W, Zhao J, Zhu C, Meng Q, Peng X, Zhang J.   +11 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A 1000 fps High-Dynamic-Range Global Shutter CMOS Image Sensor with Full Thermometer Code Current-Steering Ramp. [PDF]

Sensors (Basel)
Han L, Cheng G, Zhang X, Wang G, Pan W, Yao Y, Yu G, Zhang R, Mu S, Wu S, Bu H, Dai L, Fan B, Wang D, Fan W, Chen R.   +15 more
europepmc   +1 more source

CCD image sensor for astronomical applications(Scientific image sensors,2nd Asian Image Sensors and Imaging Systems Symposium)

ITE Technical Report, 2014
Suzuki, Hisanori, Muramatsu, Masaharu, Miyazaki, Yasuhito, Takagi, Shin'ichiro   +3 more
openaire   +1 more source