Results 161 to 170 of about 12,376,745 (263)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Pushing the boundaries of smartphone image sensors by measuring the total ozone column
, 2018 Smartphone image sensors allow more than just conventional photography and can be used for a number of scientific ...
Igoe, Damien, Parisi, Alfio
core +1 more source
Modeling Signal-to-Noise Ratio of CMOS Image Sensors with a Stochastic Approach under Non-Stationary Conditions. [PDF]
Sensors (Basel), 2023 Cherniak G +3 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Unipolar Barrier Near-Infrared 2D Photodetectors for 3D Image Sensors. [PDF]
Adv Sci (Weinh)Hong JP +21 more
europepmc +1 more source
Application of Image Sensors to Detect and Locate Electrical Discharges: A Review. [PDF]
Sensors (Basel), 2022 Riba JR.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Radiation-Tolerant PbS CQD Thin-Film Photodiode-Based SWIR Image Sensors. [PDF]
Sensors (Basel)Jin M +6 more
europepmc +1 more source
Effects of Hot Pixels on Pixel Performance on Backside Illuminated Complementary Metal Oxide Semiconductor (CMOS) Image Sensors. [PDF]
Sensors (Basel), 2023 Liu B, Li Y, Wen L, Zhang X, Guo Q.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source