Results 181 to 190 of about 621,417 (312)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Efficient Photoacoustic Image Synthesis with Deep Learning. [PDF]

Sensors (Basel), 2023
Rix T, Dreher KK, Nölke JH, Schellenberg M, Tizabi MD, Seitel A, Maier-Hein L.   +6 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Hybrid GAN-LSTM framework for diabetic foot ulcer image synthesis and automated diagnosis. [PDF]

Front Med (Lausanne)
Vina A, Prajasree G, Venkatesh S, Sankaranarayanan S, Meenakshi K, Khan AR, Imam SBS, Wahab Sait AR.   +7 more
europepmc   +1 more source

Hyperspectral screen-image-synthesis meter with scattering-noise suppression. [PDF]

Sci Rep, 2023
Yu YW, Le M, Yang TH, Chen CH, Huang PD, Wu CS, Lin CC, Lee TX, Sun CC.   +8 more
europepmc   +1 more source

Image compression by microtexture synthesis.

, 2012
Further compression gains beyond the state of the art in image coding are difficult to achieve when the pixel fidelity paradigm is retained. It is necessary to find an image representation that addresses the definitions of “irrelevance” and “redundancy” in a way that is closer to human perception.
openaire   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Artificial electrospun blood vessels

, 2016
This photograph originally appeared in the 2016 Research student photography and image competition held to celebrate National Science Week (Aug 13-21). Blurb: Native blood vessels are subject to failure, due to thrombosis formation.
Nasser Awad
core  

Cyclic 2.5D Perceptual Loss for Cross-Modal 3D Medical Image Synthesis: T1w MRI to Tau PET. [PDF]

Hum Brain Mapp
Moon J, Kim S, Chung H, Jang I, Alzheimer's Disease Neuroimaging Initiative.   +4 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source