Results 111 to 120 of about 10,261 (287)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Dissociations between word and picture naming in Persian speakers with aphasia
Frontiers in Psychology, 2014 Studies of patients with aphasia have found dissociations in their ability to read words and name pictures (Hillis & Caramazza, 1995; Hillis & Caramazza, 1991).
Mehdi Bakhtiar, Reyhane Jafari
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A Research on Street Design from Public Landscapes; Van (Turkiye) Winter City Example
Journal of Architectural Sciences and ApplicationsThe aim of this study is to reveal whether the relationship between the city and climate can be directed with a landscape design approach in order to make the use of public open spaces streets attractive and lively in winter months in the winter city ...
Betül Yılmaz, Feran Aşur
doaj +1 more source
Contextual diversity, not word frequency, determines word-naming and lexical decision times [PDF]
Word frequency is an important predictor of word-naming and lexical decision times. It is, however, confounded with contextual diversity, the number of contexts in which a word has been seen.
Baayen R.H. +5 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Nature, 1987 In a Mössbauer experiment, if a spatially-extended absorbing sample is rotated relative to a moving γ-ray source, lines of constant γ-ray Doppler shift are generated through the absorber parallel to the motion of the source. As a result, resonant absorption takes place along a series of parallel lines cutting through the absorber, where a particular ...
openaire +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source