Results 121 to 130 of about 10,261 (287)
Urban Metamorphosis: Enhancing Imageability through Vertical Hybrids
Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUATo create a vertical ecosystem of hybrid urban forms to enhance imageability. This paper proposes a transformative approach to elevate the imageability of cities through a fusion of innovative urban forms, vertical ecosystems, and sustainability ...
Ananya Gehlot, Arham Jain
doaj +1 more source
, 1980 The role of images of information (charts, diagrams, maps, and symbols) for effective presentation of facts and concepts is expanding dramatically because of advances in computer graphics technology, increasingly hetero-lingual, hetero-cultural world target populations of information providers, the urgent need to convey more efficiently vast amounts of
openaire +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Iconarp International Journal of Architecture and PlanningSpace is a fundamental component of our existence, without which we cannot live or think. During our daily lives, we perceive various components of space concurrently and we build an understanding of the environment in our memories.
Zeynep Tarçın Turgay, Alper Ünlü
doaj +1 more source
Hidden Structure and Function in the Lexicon [PDF]
, 2013 How many words are needed to define all the words in a dictionary? Graph-theoretic analysis reveals that about 10% of a dictionary is a unique Kernel of words that define one another and all the rest, but this is not the smallest such subset.
Blondin-Massé, Alexandre +5 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Linking activity and place attachment dimensions in enhancing the sense of place [PDF]
, 2007 Sense of place definition includes the point where the physical form, activity and meaning are intertwined in the people experience of a place. In urban design and place quality research, much has been discussed on the influence of the physical form ...
Dola, Kamariah, Ujang, Norsidah
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source