Results 71 to 80 of about 636,908 (298)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Comparação de softwares de análise de imagem para a determinação da área foliar.

Revista Brasileira de Meio Ambiente, 2018
A estimativa da área foliar é um componente fundamental para os modelos de desenvolvimento das plantas, pois permite compreender as adaptações ecofisiológicas perante estímulos do meio ambiente ou de práticas de manejo. Nesse sentido, objetivamos avaliar
Jhonatan Rafael Zárate-Salazar, Mirela Natália Santos, José Nailson Barros Santos, Flavio Lozano Isla   +3 more
doaj  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Comparative Evaluation of Free Web Tools ImageJ and Photopea for the Surface Area Quantification of Planar Substrates and Organisms

Diversity, 2022
Biological imaging is an essential tool to visualise and obtain reference data. In this context, the programme ImageJ has been widely used in many disciplines to determine the surface areas of planar biological samples in marine and aquatic experimental ...
Yusuf C. El-Khaled, Alexandra Kler Lago, Selma D. Mezger, Christian Wild   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Quantitative evaluation of mitochondrial dynamics during maintenance of cellular bioenergetics using ImageJ [PDF]

Scripta Medica
Background/Aim: Mitochondria are one of the most dynamic organelles essential for maintaining cellular energy demands, including execution of several vital cellular processes. This feature is attributed to rapid adaptation in morphological features which
Mehrotra Arpit, Sood Abhilasha, Kanwar Diksha   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Can biochar ameliorate phosphorus deficiency and aluminium phytotoxicity in acid soils? : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy of Applied Science in Soil Science at Massey University, Palmerston North, New Zealand [PDF]

, 2015
The use of biochar as soil amendment to enhance soil functionality is being increasingly investigated, with particular attention given to its effects on the sustainable increase of crop production and carbon (C) sequestration. To date, however, limited
Shen, Qinhua
core  

Use of sonic tomography to detect and quantify wood decay in living trees. [PDF]

, 2016
Premise of the studyField methodology and image analysis protocols using acoustic tomography were developed and evaluated as a tool to estimate the amount of internal decay and damage of living trees, with special attention to tropical rainforest trees ...
Ballesteros, Javier O, Barrick, Pablo P, Barrios-Rodriguez, Cesar A, Bonadies, Ernesto F, Burgos, Alana C, Cedeño-Sánchez, Marjorie L, Chester, Kathleen N, Diab, Jonathan H, Faircloth, Brant C, Fossatti-Caballero, Nohely J, Fábrega, Juan Pablo, García-López, Cesar G, Gilbert, Gregory S, Glenn, Travis C, Harrower, Jennifer T, Henn, Laura AW, Hershcovich, Shiran, Holub-Young, Katharine S, Hooton, Douglas A, Hubbell, Stephen P, Johnston, Daniel C, Jordan, Fulvia A, Lumpkin, Raleigh, McWilliams, Hunter A, Pérez-Suñiga, José Moises, Renteria, Sonia A, Romo, Amanda C, Russo, Natalie, Sánchez, Juan David, Thompson, Jennifer B, Trejos-Rodríguez, Mariam M, Wong, E Beatriz   +31 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source