Results 81 to 90 of about 636,908 (298)

Computed fiber evaluation of SEM images using DiameterJ

open access: yesCurrent Directions in Biomedical Engineering, 2020
Fiber materials offer a high potential for improving the surface characteristics of medical implants. For quality assurance of nano- and microfiber structures the morphology is inspected by Scanning Electron Microscopy (SEM) as a standard method.
Götz Andreas   +3 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Characterization of Focused Ion Beam Milled Lines [PDF]

open access: yes, 2012
As the nanotechnology is becoming an important aspect of science research and development, the application of the focused ion beam (FIB) technique is getting more attention. The focused ion beam is a tool for milling tiny objects.
Guo, Yingshi
core   +1 more source

Single-grain dose-distribution measurements by optically stimulated luminescence using an integrated EMCCD-based system

open access: yes, 2015
We report on the feasibility of assessing single-grain dose-distributions by using an EMCCD-based imaging system with complementary analysis software. Automated image-processing was successfully applied to compensate sample motion and for automated grain
Dornich, Kay   +5 more
core   +1 more source

Batch Processing Methods in ImageJ

open access: yes, 2022
AbstractIn this chapter you will learn how to execute a workflow on not only one image but on several images in ImageJ – a technique that is called “Batch Processing”. Various ways of doing this are possible in the Fiji distribution of ImageJ, and the characteristics of each and how-to are explained.
Klemm A, Miura K
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Post-acquisition image based compensation for thickness variation in microscopy section series

open access: yes, 2015
Serial section Microscopy is an established method for volumetric anatomy reconstruction. Section series imaged with Electron Microscopy are currently vital for the reconstruction of the synaptic connectivity of entire animal brains such as that of ...
Bogovic, John A.   +2 more
core   +1 more source

Creating Pseudocolor Images using ImageJ [PDF]

open access: yesMicroscopy Today, 2006
Abstract It is common for microscopists to examine fluorescent samples that have been exposed to a mixed set of fluorophores with specific staining properties. Images are often captured from these samples as a set, using different filter sets to isolate specific elements of the sample. Sometimes the images are captured in gray scale, and
openaire   +1 more source

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