Results 91 to 100 of about 5,775,205 (294)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

[Casernes de Qasr al-Nil (champ de Mars)], Tiré de Images, du 5 avril 1947, p. 15

, 1960
Images. [Casernes de Qasr al-Nil (champ de Mars)], Tiré de Images, du 5 avril 1947, p. 15.
Images
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Tandis que l'horloge de la citadellefonctionne celle du palais "El Tahra" est arrêtée, Tiré de Images du 21 mai 1960

, 1960
Images. Tandis que l'horloge de la citadellefonctionne celle du palais "El Tahra" est arrêtée, Tiré de Images du 21 mai 1960.
Images
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

[ancien siège des journaux al-Hilalet al-Musawwar], Tiré de Images du 14 avril 1933, p. 41

, 1960
Images. [ancien siège des journaux al-Hilalet al-Musawwar], Tiré de Images du 14 avril 1933, p. 41.
Images
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

[Camille Saint-Saëns devant le Selamlik du Palais al-Manyal en 1909]Tiré de Images, du 16 juin 1950

, 1960
Images. [Camille Saint-Saëns devant le Selamlik du Palais al-Manyal en 1909]Tiré de Images, du 16 juin 1950.
Images
core  

Statistics of gradient directions in natural images. [PDF]

, 2007
Interest in finding statistical regularities in natural images has been growing since the advent of information theory and the advancement of the efficient coding hypothesis that the human visual system is optimised to encode natural visual stimuli.
Nasrallah, A.J., Nasrallah, Alexandre James   +1 more
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source